Peer-reviewed veterinary case report
Skin problems in dogs and cats: what is cutaneous vasculitis?
By Nichols, P R et al.·Published in Veterinary dermatology·2001·Animal Allergy and Dermatology Center of Central Texas, United States·View original on PubMed →
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Original publication title: A retrospective study of canine and feline cutaneous vasculitis.
- Species:
- dog
Plain-English summary
A group of dogs and cats with skin problems caused by cutaneous vasculitis (inflammation of blood vessels in the skin) was studied to understand their symptoms and treatment responses. Many cases were idiopathic, meaning the cause was unknown, but some were linked to rabies vaccines or food allergies. Dogs with vaccine-related vasculitis responded well to a combination of prednisone and pentoxifylline, while others with different types of inflammation improved with sulfone drugs or prednisone alone. Overall, the right treatment helped many pets recover from their skin issues.
People also search for: dog skin problems treatment · cat vasculitis symptoms · prednisone for dog skin inflammation
Abstract
Twenty-one cases of cutaneous vasculitis in small animals (dogs and cats) were reviewed, and cases were divided by clinical signs into five groups. An attempt was made to correlate clinical types of vasculitis with histological inflammatory patterns, response to therapeutic drugs and prognosis. Greater than 50% of the cases were idiopathic, whereas five were induced by rabies vaccine, two were associated with hypersensitivity to beef, one was associated with lymphosarcoma and two were associated with the administration of oral drugs (ivermectin and itraconazole). Only the cases of rabies vaccine-induced vasculitis in dogs had a consistent histological inflammatory pattern (mononuclear/nonleukocytoclastic) and were responsive to combination therapy with prednisone and pentoxifylline, or to prednisone alone. Most cases with neutrophilic or neutrophilic/eosinophilic inflammatory patterns histologically did not respond to pentoxifylline, but responded to sulfone/sulfonamide drugs, prednisone, or a combination of the two.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11906650/