Peer-reviewed veterinary case report
Treatment options and outcomes for lupoid nail disease in dogs
By Mueller, Ralf S et al.·Published in Journal of the American Animal Hospital Association·2003·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: A retrospective study regarding the treatment of lupoid onychodystrophy in 30 dogs and literature review.
- Species:
- dog
Plain-English summary
Thirty dogs with a nail condition called lupoid onychodystrophy (which causes abnormal nail growth) were treated with various medications and supplements. Many dogs showed significant improvement when given a combination of doxycycline (an antibiotic) and niacinamide (a form of vitamin B3), while others did well on fatty acid supplements alone. However, some dogs experienced spontaneous remissions and recurrences, making it hard to determine the overall success of the treatments. Despite the challenges, nearly half of the dogs responded positively to the doxycycline and niacinamide combination.
People also search for: dog nail problems treatment · lupoid onychodystrophy in dogs · doxycycline for dog nail condition
Abstract
The treatment records of 30 dogs with lupoid onychodystrophy were evaluated retrospectively. Dogs were treated with fatty acid supplementation (n=18), doxycycline and niacinamide (n=12), tetracycline and niacinamide (n=10), pentoxifylline (n=6), prednisolone (n=5), azathioprine (n=1), clofazimine (n=1), or with combinations thereof. An excellent response was seen in almost half of the patients treated with tetra- or doxycycline in combination with niacinamide. Six of the dogs were maintained successfully on fatty acid supplementation. Spontaneous remissions and recurrences made evaluation of success rates difficult and emphasized the varied and often unclear etiology and natural course of the syndrome.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12617542/