Peer-reviewed veterinary case report
Dog with rare malignant salivary gland tumor in mouth and throat
By Faustino, A M & Dias Pereira, P·Published in Veterinary journal (London, England : 1997)·2007·ICBAS·View original on PubMed →
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Original publication title: A salivary malignant myoepithelioma in a dog.
- Species:
- dog
Plain-English summary
A 12-year-old female mixed breed dog was brought to the vet with a large, lobulated mass in her mouth, extending from the soft palate to the epiglottis. After examining the tissue, the vet diagnosed her with a rare type of cancer called malignant myoepithelioma, which is a tumor originating from the cells that support salivary glands. This type of tumor is uncommon in dogs, and the vet will likely discuss treatment options such as surgery or other therapies to address the cancer.
People also search for: dog mouth tumor · malignant myoepithelioma in dogs · dog salivary gland cancer treatment
Abstract
Salivary tumours are uncommon in domestic animals and there are no known previous confirmed reports of salivary tumours of myoepithelial origin in dogs. A 12-year-old female mixed breed dog was presented with a lobulated mass, composed of white-yellowish tissues, extending from soft palate to epiglottis. Histological examination revealed a neoplastic lesion consisting of a dense population of cells showing moderate pleomorphism, with pale cytoplasm and large oval nuclei, arranged in solid lobules. Mitotic activity was very high. Tumoral cells were negative for both periodic acid-Schiff reaction and Alcian blue stain and displayed strong immunohistochemical reactivity for pan-cytokeratin, muscle specific actin and myosin and focal positivity for cytokeratin 14. On the basis of the morphological, histochemical and immunohistochemical findings a diagnosis of malignant tumour of myoepithelial origin (malignant myoepithelioma) was made.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16310384/