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Peer-reviewed veterinary case report

A simple method for assessing analgesic requirements and efficacy in rodents.

Journal:
Lab animal
Year:
2009
Authors:
Wheat, Nathan J & Cooper, Dale M
Affiliation:
Covance Inc. · United States

Abstract

Evaluation of pain in the clinical setting is an ongoing challenge for veterinarians, researchers and IACUCs. Behavioral assessment, a common technique for evaluating pain, is subjective and difficult to translate into quantifiable data. The authors propose measuring changes in body weight, food consumption and water consumption as a simple and objective method for evaluating postsurgical pain and analgesic efficacy in rodents.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19543263/