Peer-reviewed veterinary case report
A step forward for stress-induced ataxia.
- Journal:
- Trends in neurosciences
- Year:
- 2022
- Authors:
- Marques, Hugo G et al.
- Affiliation:
- Neuroscience Program
Abstract
Patients with episodic ataxia type 2 (EA2) display attacks of severe incoordination and dystonia that can be triggered by stress. In a recent study, Snell, Vitenzon, Tara, and colleagues found a mechanistic pathway by which norepinephrine (NE) alters cerebellar Purkinje output to trigger attacks in a mouse model of EA2 and identified a pharmacological intervention that effectively reduces them.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/35672171/