Peer-reviewed veterinary case report
Treating fungal skin infection in cats with medicine and shampoo
By Sparkes, A H et al.·Published in Journal of feline medicine and surgery·2000·The Animal Health Trust·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: A study of the efficacy of topical and systemic therapy for the treatment of feline Microsporum canis infection.
- Species:
- cat
Plain-English summary
A group of healthy cats developed a skin infection caused by Microsporum canis, which is a type of fungus. They were treated in three different ways: one group received oral griseofulvin along with a special shampoo twice a week, another group got only the oral medication, and the last group received no treatment. The cats that received both the oral medication and the shampoo showed quicker improvement, with their infections clearing up faster than those who only received the medication or no treatment at all. This suggests that using the shampoo along with griseofulvin can be more effective for treating this fungal infection in cats.
People also search for: cat skin infection treatment · Microsporum canis in cats · griseofulvin for cat fungus · cat shampoo for fungal infection
Abstract
Microsporum canis infection was induced in 21 healthy SPF-derived cats. Once infection was established (4 weeks after inoculation) the cats were divided into three equal groups housed in separate rooms and monitored for 16 weeks. During this time, group A cats received oral griseofulvin at approximately 50 mg/kg daily and were shampooed twice weekly with a product containing chlorhexidine and miconazole. Group B cats were treated with griseofulvin alone, and group C cats served as untreated controls. The cats were examined on a weekly basis and the severity of lesions was scored semi-quantitatively. In addition, hair samples were collected from each cat on a weekly basis by the MacKenzie brush technique and by the sticky-tape method. A semi-quantitative scoring system was also used for the assessment of fungal (M canis) growth. Generally, significant differences in clinical scores were not seen between the groups although at weeks 3, 4 and 11 there was a significant difference (P< or =0.015) with cats in group A having significantly lower median scores than those in group C. Median times to clinical resolution (return of clinical scores to zero) in groups A, B and C were at treatment weeks 2, 9 and 12, respectively (P>0.05). Median times for mycological resolution (persistently negative culture results) for groups A, B and C were at treatment weeks 2, 9 and 12, respectively, for the MacKenzie brush technique and at weeks 4, 8 and 12 for the sticky-tape technique. For both these results, the groups differed significantly (P< or =0.001) and in both instances group A had significantly more rapid resolution than groups B or C. Median culture scores were significantly different between the three groups using one or both of the sampling techniques at week 2 through to week 12 of treatment with median scores for either group A alone, or groups A and B being significantly lower than group C (P< or =0.026). These results showed a benefit from the addition of twice-weekly chlorhexidine-miconazole shampooing to systemic griseofulvin therapy alone in the treatment of M canis infected cats.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11716608/