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Peer-reviewed veterinary case report

A suprasellar germ cell tumor in a 16-month-old Wagyu heifer calf.

Journal:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Year:
2012
Authors:
Brooks, Aimee N et al.
Affiliation:
The Ohio State University Veterinary Medical Center · United States
Species:
dog

Abstract

A 16-month-old Wagyu heifer calf presented for depression, inappetence, and polyuria/polydipsia. Physical examination revealed that the heifer calf was mentally dull, subjectively small for her age, bradycardic, and hypothermic and had bilateral nasal discharge. Laboratory tests revealed marked serum and cerebrospinal fluid hypernatremia and hyperchloremia with increased cerebrospinal fluid protein. The heifer calf was treated with Ringer solution intravenously for dehydration and electrolyte abnormalities, and with 1 dose each of thiamine and penicillin. Clinical deterioration prompted the owner to elect humane euthanasia. Necropsy revealed a mass lesion in the suprasellar region. Histopathology was consistent with a suprasellar germ cell tumor; the mass stained positive on immunohistochemistry for cytokeratin, vimentin, and c-kit. Suprasellar germ cell tumors have previously been reported in human beings and dogs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22529131/