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Peer-reviewed veterinary case report

Feline leukemia virus infection rates in cats from Harare Zimbabwe

By Muchaamba, Francis et al.·Published in Journal of the South African Veterinary Association·2014·View original on PubMed

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Original publication title: A survey of feline leukaemia virus infection of domestic cats from selected areas in Harare, Zimbabwe.

Species:
cat

Plain-English summary

A study found that 41% of domestic cats tested in Harare, Zimbabwe, were infected with feline leukemia virus (FeLV), which can weaken their immune system and lead to serious health issues. Cats that were intact (not neutered), lived with other cats, or had outdoor access were more likely to be infected. The researchers did not find specific blood changes related to the infection, but the high rate of FeLV suggests that more control measures are needed to protect cats in the area. If your cat shows signs of illness, it's important to talk to your veterinarian about testing for FeLV and possible preventive measures.

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Abstract

A cross-sectional study was conducted to detect the feline leukaemia virus (FeLV) p27 antigen and to determine risk factors and the haematological changes associated with infection in domestic cats in Zimbabwe. Sera were collected for detection of the p27 antigen, urea, creatinine, alanine aminotransferase and gamma-glutamyl transferase levels, whilst whole blood was collected for haematology. FeLV p27 antigen was detected using a rapid enzyme-linked immunosorbent assay (ELISA) test kit. Data on risk factors were analysed using a logistic regression model. Of the 100 cats tested, 41% (95% CI: 31.19% - 50.81%) (41/100) were positive for the FeLV p27 antigen. Sex and health status of cats were not significantly (p > 0.05) associated with infection. Intact cats (OR = 9.73), those living in multicat housing (OR = 5.23) and cats that had access to outdoor life (OR = 35.5) were found to have higher odds of infection compared with neutered cats, those living in single-cat housing, and without access to outdoor life, respectively. Biochemistry and haematology revealed no specific changes. The results showed that FeLV infection was high in sampled cats, providing evidence of active infection. Thus, it would be prudent to introduce specific control measures for FeLV infection in Zimbabwe.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25686080/