Peer-reviewed veterinary case report
Dog's tongue and muzzle swelling after IV mannitol during surgery
By Seddon, Kathleen et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2025·The Animal Referral Centre·View original on PubMed →
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Original publication title: A suspected anaphylactoid reaction to intravenous administration of mannitol in a dog.
- Species:
- dog
Plain-English summary
A 1-year-old neutered female French Bulldog had a serious reaction while receiving an intravenous medication called mannitol during surgery for a spinal issue. Midway through the treatment, her tongue and face swelled significantly, causing concern for her airway. Fortunately, the veterinary team quickly administered medications to reduce the swelling, and her vital signs remained stable throughout the incident. By the end of her recovery period, the swelling had completely resolved, and she was able to breathe normally without any complications.
People also search for: dog tongue swelling after surgery · French Bulldog allergic reaction · mannitol side effects in dogs
Abstract
OBJECTIVE: To describe a case of a suspected anaphylactoid reaction to mannitol in a dog. CASE SUMMARY: A 1-year-old, neutered female French Bulldog was anesthetized for a T12-T13 dorsal laminectomy surgery for a previously diagnosed spinal arachnoid diverticulum. Perioperatively, the spinal cord appeared grossly edematous, and IV mannitol administration was elected. Midway through administration of mannitol, peracute erythema and angioedema were noted around the patient's tongue, muzzle, and paws. The dog's tongue grew to approximately twice its normal size. All vital parameters remained within normal limits. The dog was treated intravenously with dexamethasone and intramuscularly with mepyramine maleate. The remainder of the anesthetization was uneventful. The swelling completely resolved during the 2-hour recovery period, but careful management of the enlarged tongue was required to prevent airway occlusion. NEW OR UNIQUE INFORMATION PROVIDED: This is the first reported case of a suspected anaphylactoid reaction to IV administration of mannitol in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39558455/