Peer-reviewed veterinary case report
Dog with suspected allergic reaction to propofol anesthesia
By Del Prete, Tommaso & Scarabelli, Stefania·Published in Topics in companion animal medicine·2021·Clinica Veterinaria Malpensa/Anicura, Italy·View original on PubMed →
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Original publication title: A Suspected Anaphylactoid Reaction to Propofol in a Dog.
- Species:
- dog
Plain-English summary
A 14-year-old Shih Tzu experienced a serious allergic reaction to the anesthetic propofol while undergoing surgery for a severe uterine infection. After being put under anesthesia, the dog showed signs of distress, including difficulty breathing and a slow heart rate, leading the veterinarians to stop the procedure. Despite efforts to treat the dog with fluids and steroids, the situation worsened, and the owner ultimately chose to euthanize the dog due to the costs of continued care.
People also search for: dog allergic reaction to anesthesia · Shih Tzu surgery complications · propofol side effects in dogs
Abstract
Anaphylactoid reactions to anaesthetic drugs are rarely reported in veterinary medicine. The aim of this report is to describe a suspected anaphylactic reaction to propofol in a 14 years old Shih-Tzu undergoing general anaesthesia for ovariohysterectomy due to a pyometra. The anesthetic protocol included intramuscular methadone for premedication and fentanyl, midazolam and propofol intravenously for co-induction. At endotracheal intubation, the glottis appeared subjectively thickened. Shortly after induction and endotracheal intubation, desaturation, hypercapnia and bradycardia occurred; chest compliance at manual ventilation was poor and peripheral pulses were weak. The procedure was aborted. Pulmonary oedema was diagnosed at thoracic radiography and a cardiogenic origin was excluded via echocardiography. Fluid therapy and glucocorticoids were administered, and mechanical ventilation was started in the intensive care unit. Two hours later, the owner opted for euthanasia due to financial constraints.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33957306/