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Peer-reviewed veterinary case report

A suspected new species of Leishmania, the causative agent of visceral leishmaniasis in a Thai patient.

Journal:
International journal for parasitology
Year:
2008
Authors:
Sukmee, Theerayudh et al.
Affiliation:
Bureau of Epidemiology Ministry of Public Health
Species:
cat

Plain-English summary

Researchers have identified a possible new type of Leishmania, which is a parasite that causes visceral leishmaniasis, in a man from Southern Thailand. This case is notable because it's the third reported instance of this disease occurring in people living in that area. Tests showed that this new species is different from other known types of Leishmania. Additionally, antibodies indicating exposure to Leishmania were found in nine domestic cats, suggesting that they may also be affected. Given the rising concern about this disease, experts recommend conducting a large-scale study to better understand its spread and impact on public health in Thailand.

Abstract

A suspected new species of Leishmania is described as the causative agent of the third reported case of autochthonous visceral leishmaniasis in a Thai man living in Southern Thailand. The results of PCR-restriction fragment length polymorphism and sequence analysis of the internal transcribed spacer 1 of ssrRNA and the mini-exon genes were different from those of previously reported Leishmania species. A direct agglutination test (DAT) revealed that antibody against Leishmania infection was detected in nine domestic cats. No potential vectors could be identified. A large-scale epidemiological survey of leishmaniasis should be urgently conducted since visceral leishmaniasis is considered an emerging disease of public health concern in Thailand.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18262531/