Peer-reviewed veterinary case report
Dog with dysautonomia signs improves after metoclopramide
By Wise, L A & Lappin, M R·Published in Journal of the American Veterinary Medical Association·1991·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: A syndrome resembling feline dysautonomia (Key-Gaskell syndrome) in a dog.
- Species:
- dog
Plain-English summary
A 1-year-old dog was brought in with symptoms like diarrhea, vomiting, and urinary incontinence, which indicated a problem with its autonomic nervous system. The vet diagnosed the dog with dysautonomia, a condition that affects automatic body functions. After starting treatment with metoclopramide and bethanechol, the dog's appetite and mood improved within a day, and its tear production and vomiting frequency also got better. Over the next three weeks, the dog's bladder control and anal tone improved significantly.
People also search for: dog vomiting and diarrhea · dysautonomia in dogs · treatment for dog urinary incontinence · dog appetite improvement · dog eye problems treatment
Abstract
Dysautonomia, or autonomic nervous system dysfunction, was diagnosed in a 1-year-old dog. Clinical signs of disease included diarrhea, vomiting, prolapse of nictitating membranes, and urinary incontinence. Bilateral keratoconjunctivitis sicca, xerostomia, and decreased anal sphincter tone were also observed. On the basis of response to atropine, results of intradermal histamine testing and gastric motility studies, and ocular response to parasympathomimetics and sympathomimetics (direct and indirect acting), autonomic nervous system function was determined to be abnormal. Treatment with metoclopramide hydrochloride and bethanechol chloride resulted in improved attitude, appetite, Schirmer tear test response, and decrease in frequency of vomiting within 24 hours. Bladder function and anal tone improved within 3 weeks.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1679426/