Peer-reviewed veterinary case report
A systematic approach to tuberculosis vaccine development.
- Journal:
- Cell
- Year:
- 2025
- Authors:
- Seshadri, Chetan
- Affiliation:
- Department of Medicine · United States
Abstract
M. tuberculosis is once again the leading infectious cause of death worldwide despite the existence of a licensed vaccine (BCG). In this issue of Cell, Vidal et al. systematically evaluate 42 candidate antigens and develop a trivalent mRNA vaccine that demonstrates effective and durable protection from tuberculosis in several mouse models. This vaccine also enhances protection conferred by BCG.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/41308617/