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Peer-reviewed veterinary case report

No kidney ultrasound artifact seen in cats with chronic kidney disease

By Chou, Ping-Hsien et al.·Published in The veterinary quarterly·2021·Department of Veterinary Medicine·View original on PubMed

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Original publication title: Absence of renal cortical anisotropic backscattering artifact in feline chronic kidney disease.

Species:
cat

Plain-English summary

A study found that cats with chronic kidney disease (CKD) often show a specific ultrasound pattern called renal cortical anisotropic backscattering artifact (CABA) that is absent in healthy cats. Researchers looked at ultrasound images from 40 cats with CKD and 36 healthy cats, discovering that the absence of this ultrasound artifact was strongly linked to CKD. This finding could help veterinarians diagnose CKD more effectively, as the absence of renal CABA had high sensitivity and specificity for detecting the disease. This means that if your cat is diagnosed with CKD, this ultrasound method could be a useful tool for evaluation.

People also search for: cat kidney disease ultrasound · chronic kidney disease in cats · feline CKD diagnosis methods

Abstract

Renal cortical anisotropy backscattering artifact (CABA) is a focal hyperechoic region where the tubules are parallel to the incident ultrasound beam, reflecting most of the beams to the transducer. To investigate the association between chronic kidney disease (CKD) and the absence of renal CABA in cats. Ultrasonographic renal images of 40 cats with CKD (stage II-IV) and 36 clinically healthy cats were blindly evaluated by two observers to determine the visibility of renal CABA. Inter- and intraobserver agreements were evaluated using McNemar's test. The association between the absence of renal CABA and CKD was assessed using Fisher's exact test. Excellent intraobserver and substantial interobserver agreements were demonstrated. A significant association (< .0001) between absent renal CABA and CKD stage was revealed in all cats. Cats with CKD had an increased risk of the absence of renal CABA (Odds ratio, 56.0; 95% CI, 13.8-227.0) compared with the clinically healthy cats. The absence of renal CABA revealed 87.5% sensitivity and 88.9% specificity to detect CKD in all cats, and 91.7% sensitivity and 83.3% specificity in aged cats. Our study demonstrated a correlation between feline CKD and the absence of renal CABA, providing a feasible and alternative method for feline CKD evaluation.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34112054/