Peer-reviewed veterinary case report
Cat acceptance and owner compliance with atenolol tablet
By Khor, Kuan Hua et al.·Published in Journal of feline medicine and surgery·2012·School of Veterinary Science, Australia·View original on PubMed →
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Original publication title: Acceptability and compliance of atenolol tablet, compounded paste and compounded suspension prescribed to healthy cats*.
- Species:
- cat
Plain-English summary
A group of 13 healthy cats were given atenolol, a medication for heart problems, in three different forms: a tablet, a compounded paste, and a compounded suspension. Owners reported their experiences with each form over six days, noting how well their cats accepted the medication. While the compounded suspension had the fewest missed doses, most owners preferred the tablet form. Overall, all three options were accepted by the cats, but the tablet was the favorite among owners. Further research is needed to ensure the compounded forms are stable and effective.
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Abstract
This study was designed to evaluate the cats' acceptance and compliance of the owners and cats towards an extemporaneously prepared palatable compounded atenolol (paste and suspension) formulation in comparison to the commercially obtained tablet, in a randomised, cross-over study design.The three formulations were prescribed twice daily for 6 days to 13 healthy privately-owned cats of 13 different owners, with varying levels of experience in medicating cats. Daily compliance was evaluated via an owner-completed diary, completed after each dose administered. Owner's experience and preference of the formulation was evaluated via questionnaires given prior to, at the end of each treatment protocol, and upon completion of the study. Although compounded suspension was association with fewest missed doses, the majority of cat owners expressed a preference for the divided tablet. Atenolol tablets, compounded paste and suspension acceptance and compliance were comparable. Further work is now required to assess the amount and stability of the active ingredient and the robustness of the paste and suspension formulations prior to any bioavailability comparisons between the formulations.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22314084/