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Peer-reviewed veterinary case report

Accumulation of L-type bovine prions in peripheral nerve tissues.

Journal:
Emerging infectious diseases
Year:
2010
Authors:
Iwamaru, Yoshifumi et al.
Affiliation:
National Institute of Animal Health · Japan

Abstract

We recently reported the intraspecies transmission of L-type atypical bovine spongiform encephalopathy (BSE). To clarify the peripheral pathogenesis of L-type BSE, we studied prion distribution in nerve and lymphoid tissues obtained from experimentally challenged cattle. As with classical BSE prions, L-type BSE prions accumulated in central and peripheral nerve tissues.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20587193/