Peer-reviewed veterinary case report
Day blindness and color blindness in three sibling Labrador
By Dixon, Christopher J·Published in Veterinary ophthalmology·2016·Veterinary Vision Ophthalmic Referrals, United Kingdom·View original on PubMed →
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Original publication title: Achromatopsia in three sibling Labrador Retrievers in the UK.
- Species:
- dog
Plain-English summary
Three sibling Labrador Retrievers were found to have achromatopsia, a condition that causes day blindness. The dogs struggled to see in bright light and had difficulty navigating obstacles outdoors. One dog had cataracts removed, but this did not improve its vision. Tests showed that the dogs lacked a normal response from the cone cells in their eyes, which are responsible for color vision. Unfortunately, there were no known genetic mutations found that could explain their condition.
People also search for: Labrador Retriever day blindness · achromatopsia in dogs · dog cataract surgery outcome
Abstract
Achromatopsia was identified in three Labrador Retriever littermates. The dogs demonstrated day blindness, negotiating obstacles under low-light conditions, but apparently blind when outdoors. One of the dogs presented with immature bilateral diffuse posterior cortical cataracts and clinical signs of day blindness became apparent following cataract extraction surgery. Electroretinography demonstrated an absence of a cone photoreceptor response to a bright stimulus and a flicker response of 30 Hz in all three dogs. No fundic lesions have been apparent ophthalmoscopically in any of the dogs as the initial presentation of each case. No abnormalities were detected with DNA screening for known mutations of the CNGB3 gene in any of the dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25752464/