Peer-reviewed veterinary case report
Dog with bleeding and clotting factor deficiency
By Hausmann, Lisa et al.·Published in Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·2016·Lisa Hausmann·View original on PubMed →
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Original publication title: [Acquired von-Willebrand factor and factor-VIII deficiencies caused by angiostrongylosis in a dog].
- Species:
- dog
Plain-English summary
An 8-year-old male Australian Shepherd was brought in with bleeding from his lip and internal bleeding in the abdomen. Blood tests showed he had low platelet counts and anemia, but initial scans didn’t reveal the source of the bleeding. After a plasma transfusion helped stabilize him temporarily, further tests identified a severe deficiency in von Willebrand factor and factor VIII, both linked to an infection from a parasite called Angiostrongylus vasorum. After treatment with fenbendazole, his blood factors returned to normal, and he recovered well.
People also search for: dog bleeding from lip · Australian Shepherd anemia treatment · Angiostrongylus vasorum in dogs
Abstract
An 8-year-old male Australian Shepherd was presented with bleeding from the lip and hemoabdomen. Hematology demonstrated marked thrombocytopenia and anemia. Abdominal ultrasound followed by laparotomy did not detect the cause of bleeding. Plasma transfusion resulted in temporary stabilization. Severe von-Willebrand factor deficiency and factor-VIII deficiency were diagnosed. After subsequent bleeding episodes, infection with Angiostrongylus vasorum was found in both a fecal parasitological examination and by PCR from EDTA-blood. Following successful therapy with fenbendazole, von Willebrand factor and factor VIII were within the normal range. This is the second case report of an acquired von-Willebrand-factor deficiency associated with Angiostrongylus-vasorum infection in a dog, and the first case report with concurrent factor-VIII deficiency.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27189252/