Peer-reviewed veterinary case report
Acute bacterial cystitis in dogs does not cause bladder cell DNA
By Alves, A et al.·Published in Veterinary pathology·2004·Departamento de Clí, Brazil·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Acute bacterial cystitis does not cause deoxyribonucleic acid damage detectable by the alkaline comet assay in urothelial cells of dogs.
- Species:
- dog
Plain-English summary
A group of dogs with acute bacterial cystitis (a bladder infection) was studied to see if the infection caused any DNA damage in their bladder cells. The researchers found that the infection, mainly caused by Staphylococcus and E. coli bacteria, did not lead to any detectable DNA damage. This means that while these dogs had a bladder infection, it didn't seem to affect their DNA. The dogs were treated for their infection, and the study suggests that acute bacterial cystitis is not linked to DNA damage.
People also search for: dog bladder infection treatment · symptoms of cystitis in dogs · does cystitis cause DNA damage in dogs
Abstract
Considering the high incidence of dogs with acute bacterial cystitis (BC) and the relationship among inflammation, genotoxicity, and carcinogenesis, we conducted a case-control study comparing the frequency of deoxyribonucleic acid (DNA) lesions assessed by the comet assay between disease-free animals (13 males and 13 females) and cytology-confirmed cases of acute BC (12 males and 12 females), which was mainly caused by Staphylococcus sp. (40%) and Escherichia coli (35%). The results show no increase in DNA damage in cells obtained by bladder washings and no influence of age, sex, and breed due to acute BC. In conclusion, DNA damage was seemingly not associated with the infection by specific bacteria.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15133185/