Peer-reviewed veterinary case report
Pug dog vomiting and unsteady after joint supplement overdose causing
By Borchers, Angela et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2014·William R. Pritchard Veterinary Medical Teaching Hospital (Borchers, United States·View original on PubMed →
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Original publication title: Acute enteral manganese intoxication with hepatic failure due to ingestion of a joint supplement overdose.
- Species:
- dog
Plain-English summary
A 5-year-old female spayed Pug was brought in for vomiting and unsteady movements after accidentally eating about 100 joint supplement tablets. Unfortunately, she developed severe liver failure and had to be euthanized six days later due to the worsening condition. Tests revealed dangerously high levels of manganese in her liver and kidneys, indicating that the overdose from the supplements caused significant damage.
People also search for: dog vomiting after joint supplement · Pug liver failure symptoms · manganese toxicity in dogs
Abstract
Manganese is a ubiquitous, essential trace element and a common ingredient of joint supplement tablets. Little information is known about the inherent toxic potential if ingested at higher doses. A 5-year-old female spayed Pug dog presented for evaluation of vomiting and ataxia after accidental ingestion of approximately 100 joint supplement tablets. The dog developed acute hepatic failure and was euthanized 6 days after presentation due to progression of the disease. Necropsy showed severe acute hepatic necrosis. Liver and kidney samples were submitted for toxicology analysis, results of which showed severely elevated manganese concentrations in the liver and kidneys.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25080444/