Peer-reviewed veterinary case report
Dog with sudden liver rupture and internal bleeding after allergic
By Padmanabhan, Ashok et al.·Published in Veterinary medicine and science·2024·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Acute hepatic rupture causing hemoperitoneum in a dog with anaphylaxis.
- Species:
- dog
Plain-English summary
A 2-year-old spayed female Siberian Husky suddenly became lethargic, collapsed, and experienced vomiting and bloody diarrhea. Despite emergency treatment, including blood transfusions, her condition worsened, leading to cardiac arrest. The dog was revived but sadly had to be euthanized later. A necropsy revealed that she had a severe internal bleeding due to a rupture in her liver, likely triggered by an allergic reaction (anaphylaxis). This case highlights the serious complications that can arise from anaphylaxis in dogs.
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Abstract
A 2-year-old spayed female Siberian Husky was presented with a history of acute onset lethargy, collapse, haematochezia and vomiting. The patient was severely tachycardic and hypotensive. Point-of-care ultrasound revealed gallbladder wall thickening and peritoneal effusion consistent with haemorrhage on subsequent abdominocentesis. Despite attempted medical stabilization over the course of several hours, including blood products and multiple autotransfusions, the patient progressed to cardiopulmonary arrest. The dog was successfully resuscitated but was subsequently euthanized. Necropsy revealed a severe, acute hemoperitoneum secondary to rupture of the left lateral liver lobe. A tear in the hepatic capsule was identified along with a large hematoma. A single adult nematode, consistent with Dirofilaria immitis, was found in a pulmonary vessel in the right caudal lung lobe. The remaining necropsy findings were supportive of the clinical diagnosis of anaphylaxis. This report details a case, with necropsy findings, supporting a diagnosis of anaphylaxis and severe, refractory hemoperitoneum resulting from hepatic rupture. Acute hepatic rupture should be considered in cases of anaphylaxis-related hemoperitoneum.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38403981/