Peer-reviewed veterinary case report
Greyhound with muscle breakdown after albuterol overdose
By Granfone, Marcella & Walker, Julie M·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2021·School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Acute nontraumatic rhabdomyolysis in a Greyhound after albuterol toxicosis.
Plain-English summary
A 4-year-old neutered male Greyhound was brought in after being exposed to albuterol, a medication that can be toxic in high doses. The dog showed serious symptoms, including muscle pain and weakness, and required mechanical ventilation due to breathing problems. Unfortunately, despite treatment, the dog developed severe complications like kidney injury and heart issues, and ultimately had to be euthanized after six days. This case highlights the dangers of albuterol toxicity in pets.
People also search for: Greyhound albuterol toxicity · dog muscle pain after medication · dog kidney injury treatment
Abstract
OBJECTIVE: To describe the clinical features of rhabdomyolysis due to albuterol toxicosis in a Greyhound. CASE SUMMARY: A 4-year-old neutered male Greyhound was presented for albuterol toxicosis leading to severe hypokalemia and respiratory paralysis. After 3 hours of mechanical ventilation, pigmenturia and marked enlargement, firmness, and pain of the left thigh muscles were noted. Severe hyperkalemia and cardiac arrhythmias were identified after turning the patient. After discontinuation of mechanical ventilation, other muscles became involved, and the patient developed acute kidney injury and concern for multiple organ dysfunction syndrome over the next 5 days. On day 6, the patient was euthanized, and necropsy revealed myocardial and skeletal muscle necrosis, myoglobinuria, and acute tubular degeneration. NEW OR UNIQUE INFORMATION PROVIDED: To the authors' knowledge, this is the first case of albuterol toxicosis leading to rhabdomyolysis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34450682/