Peer-reviewed veterinary case report
Adaptive immunity-dependent intestinal hypermotility contributes to host defense against Giardia spp.
- Journal:
- Infection and immunity
- Year:
- 2006
- Authors:
- Andersen, Yolanda S et al.
- Affiliation:
- Department of Medicine 0665 · United States
Abstract
Humans infected with Giardia exhibit intestinal hypermotility, but the underlying mechanisms and functional significance are uncertain. Here we show in murine models of giardiasis that small-intestinal hypermotility occurs in a delayed fashion relative to peak parasite burden, is dependent on adaptive immune defenses, and contributes to giardial clearance.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16552082/