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Peer-reviewed veterinary case report

Adenomatous polyp with intestinal metaplasia of the esophagus (Barrett esophagus) in a dog.

Journal:
Veterinary pathology
Year:
2010
Authors:
Gibson, C J et al.
Affiliation:
Department of Biomedical Sciences · United States
Species:
dog

Abstract

Multiple endoscopic biopsy specimens of esophageal mucosa were received from a 13-year-old castrated male standard Poodle. The dog was presented for painful swallowing. Endoscopically, the distal aspect of the esophagus was inflamed with a polypoid mass that protruded into the esophageal lumen. Histologically, the stratified squamous epithelium overlying the mass and lining the adjacent esophageal mucosa was replaced by papillary projections covered by columnar epithelium with goblet cells supported by a fibrous stroma. This article reports a case of spontaneous esophageal adenomatous polyp with intestinal metaplasia (Barrett esophagus) and reviews the pathogenesis of esophageal metaplasia and adenocarcinoma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20080491/