Peer-reviewed veterinary case report
Dog with chronic vomiting diagnosed with esophageal adenosquamous
By Okanishi, H et al.·Published in The Journal of small animal practice·2015·Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Adenosquamous carcinoma of the oesophagus in a dog.
- Species:
- dog
Plain-English summary
A 6-year-old mixed-breed male dog was brought to the vet because he had been vomiting and regurgitating for a long time. An examination showed that his esophagus was swollen and had multiple abnormal growths. Tests revealed he had a type of cancer called adenosquamous carcinoma, which likely developed due to ongoing irritation from his vomiting. Unfortunately, this type of cancer can be serious, and the treatment options would depend on the specific case and overall health of the dog.
People also search for: dog vomiting and regurgitation · esophageal cancer in dogs · treatment for dog cancer
Abstract
A six-year-old mixed-breed male dog weighing 7.0 kg was presented with chronic vomiting and regurgitation. Endoscopic examination revealed prominent oesophageal dilation in the thoracic region, multiple small greyish-white nodules over the oesophageal lumen and cauliflower-like masses in the caudal oesophagus. Histopathological studies revealed a characteristic pattern of coexisting elements of infiltrating adenocarcinoma and squamous cell carcinoma. Immunohistochemical staining with anti-cytokeratin AE1 + AE3 was positive in both types of neoplastic cells. Neoplastic glandular cells stained positively for cytokeratin 8 while neoplastic squamous cells stained positively for cytokeratin 5/6. On the basis of these findings, the dog was diagnosed with oesophageal adenosquamous carcinoma. The case history and findings suggest that the malignancy might have developed from Barrett's oesophagus following irritation of the oesophageal mucosa due to chronic vomiting and regurgitation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25622695/