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Peer-reviewed veterinary case report

Dog with cancerous tumor on upper eyelid causing eye problems

By Nardi, Samanta et al.·Published in Topics in companion animal medicine·2020·Department of Veterinary Sciences, Italy·View original on PubMed

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Original publication title: Adenosquamous Carcinoma of the Upper Eyelid in a Dog.

Species:
dog

Plain-English summary

A 12-year-old male mongrel dog was brought to the vet because of a growing mass on his right upper eyelid that had been present for six months. The mass was ulcerated and caused some redness in the eye area. After thorough testing, including blood work and imaging, the vet diagnosed the dog with an eyelid adenosquamous carcinoma, a type of skin cancer. This case is notable as it's the first reported instance of this specific cancer in a dog. Treatment options would typically involve surgical removal of the mass, and the vet would discuss the best approach based on the dog's overall health.

People also search for: dog eyelid mass treatment · dog skin cancer symptoms · why is my dog’s eye red

Abstract

A 12-year-old, male mongrel dog was presented for a 6-month history of a progressive eyelid mass of the right upper eyelid. The dog's medical history reported long-term bilateral topical application of 0.03% tacrolimus ophthalmic ointment for third eyelid plasmoma and treatment cycles with systemic corticosteroids for a long-standing atopic dermatitis. Complete physical and ophthalmologic examination of the dog as well as complete blood count, serum biochemical analysis, urinalysis, thoracic radiographs, and abdominal ultrasonography were performed. The mass involved the skin and the margin of the upper eyelid, which was ulcerated. Conjunctival hyperemia, and the thickening and partial depigmentation of the third eyelid due to plasmoma were present. The plasmoma was observed bilaterally. Histological examination of the eyelid mass showed an invasive proliferation of malignant epithelial cells with intermixing of both adenocarcinomatous and malignant squamous cell components. An eyelid adenosquamous carcinoma was diagnosed. To the best of the authors' knowledge, this is the first report on an adenosquamous carcinoma of the eyelid in a dog. Immunosuppression has been found to be a significant clinical risk factor for cutaneous adenosquamous carcinoma in humans and was considered a possible risk factor for this dog.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32690283/