Peer-reviewed veterinary case report
Dog with intestinal carcinoid tumor treated successfully
By Spugnini, Enrico P et al.·Published in In vivo (Athens, Greece)·2008·S.A.F.U. Department, Italy·View original on PubMed →
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Original publication title: Adjuvant carboplatin for the treatment of intestinal carcinoid in a dog.
- Species:
- dog
Plain-English summary
A 10-year-old male dog was brought to the vet with constipation and difficulty passing stool for two days. During the exam, the vet found the dog was depressed and had a painful abdomen, revealing a large mass in the intestines. The mass was surgically removed and diagnosed as an intestinal carcinoid tumor. After surgery, the dog received four doses of a chemotherapy drug called carboplatin and showed no side effects. Remarkably, the dog has been in remission for 18 months and continues to be monitored every three months.
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Abstract
A ten-year-old castrated male dog was presented due to a two-day history of constipation and tenesmus. At physical examination, the dog was depressed and unresponsive. Aggressive behavior was elicited by deep abdominal palpation and a mass was detected during the examination. Imaging studies evidenced a large jejunal mass. The lesion (6 cm in diameter) was surgically removed. The histopathology report gave a diagnosis of completely excised intestinal carcinoid. The patient recovered well from the procedure and was scheduled for adjuvant chemotherapy. The dog received four doses of carboplatin (300 mg/m2) every three weeks without showing signs of toxicity. The dog is still in remission after 18 months and is reassessed on a three-month schedule. This report represents the first description of long-term control of intestinal carcinoid in the dog and the first of adjuvant chemotherapy for this rare and aggressive neoplasm.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19181003/