Peer-reviewed veterinary case report
Dog with anal sac cancer treated successfully with electrochemotherapy
By Spugnini, Enrico P et al.·Published in In vivo (Athens, Greece)·2008·S.A.F.U. Department, Italy·View original on PubMed →
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Original publication title: Adjuvant electrochemotherapy for incompletely excised anal sac carcinoma in a dog.
- Species:
- dog
Plain-English summary
A 10-year-old mixed-breed dog was diagnosed with anal sac gland carcinoma (a type of cancer) after surgery to remove the tumor was only partially successful. To treat the remaining cancer cells, the dog underwent two sessions of electrochemotherapy, which involved using a drug called cisplatin activated by electrical pulses to target the tumor. The treatment was well-tolerated, with no side effects noted, and the dog has been cancer-free for 18 months since the therapy. This approach shows promise as a safe and effective option for managing this aggressive cancer.
People also search for: dog anal sac cancer treatment · electrochemotherapy for dogs · dog cancer remission after surgery
Abstract
Canine anal sac gland carcinoma (ASGC) is a frequently described neoplasm that is highly aggressive and can frequently lead to metastatic spread. In this paper, we describe the successful treatment of an incompletely excised ASGC by using cisplatin selectively driven within the tumor cells by trains of biphasic pulses. The dog received two courses of electrochemotherapy 14 days apart. Neither systemic nor local toxicities were detected during the whole course of therapy. The dog is still in complete remission after 18 months. Electrochemotherapy is a safe and efficacious adjuvant therapy for ASGC and warrants further investigation in order to standardize its protocols.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18396781/