Peer-reviewed veterinary case report
Administration of probiotic kefir to mice with Clostridium difficile infection exacerbates disease.
- Journal:
- Anaerobe
- Year:
- 2016
- Authors:
- Spinler, Jennifer K et al.
- Affiliation:
- Department of Pathology · United States
- Species:
- rodent
Abstract
Lifeway(®) kefir, a fermented milk product containing 12 probiotic organisms, is reported to show promise as an alternative to fecal microbiota transplantation for recurrent Clostridium difficile infection (CDI). We employed a murine CDI model to study the probiotic protective mechanisms and unexpectedly determined that kefir drastically increased disease severity. Our results emphasize the need for further independent clinical testing of kefir as alternative therapy in recurrent CDI.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27180007/