Peer-reviewed veterinary case report
Dog with adrenal gland tumor causing abdominal pain and fever
By Semzenisi, Ecaterina et al.·Published in Frontiers in veterinary science·2026·Department of Pathology·View original on PubMed →
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Original publication title: Adrenal gland adenoma with myelolipoma in a canine patient: a rare case report and diagnostic insights.
- Species:
- dog
Plain-English summary
A 7-year-old male Pekingese was brought to the vet with sudden abdominal pain and fever. Tests showed a mass on his right adrenal gland, which is a rare type of tumor. The dog underwent surgery to remove the adrenal gland, and the tissue analysis confirmed it was a benign tumor with some unusual fat and blood cell components. After the surgery, the dog recovered well and has not had any issues in the year since.
People also search for: Pekingese abdominal pain · dog adrenal gland tumor treatment · what to expect after dog surgery
Abstract
Adrenal gland tumors are uncommon in dogs, and the simultaneous presence of epithelial and mesenchymal neoplasms within a single adrenal gland is exceptionally rare. We describe a rare case of an adrenocortical adenoma associated with a myelolipoma in a 7-year-old male Pekingese dog presented with acute abdominal pain and fever. Diagnostic imaging identified a well-defined mass in the right adrenal gland, with no evidence of vascular invasion or metastatic disease. Surgical adrenalectomy was subsequently performed. Histopathological evaluation revealed a well-circumscribed adrenocortical adenoma containing an intratumoral myelolipomatous component composed of mature adipose tissue and trilineage hematopoietic elements. Immunohistochemical analysis demonstrated Melan A positivity in the adenomatous component, while the myelolipomatous tissue showed diffuse vimentin expression and lacked Melan A immunoreactivity. The postoperative course was uneventful, and no recurrence was detected at one-year follow-up. This case underscores the diagnostic complexity of heterogeneous adrenal masses in dogs and highlights the essential role of histopathology and immunohistochemistry in the accurate identification of rare mixed adrenal lesions.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41938769/