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Peer-reviewed veterinary case report

Adverse Effects of Antimicrobial Drugs Use in Horses.

Journal:
The Veterinary clinics of North America. Equine practice
Year:
2025
Authors:
Gomez, Diego E & Johnson, Jessica P
Affiliation:
Department of Internal Medicine
Species:
horse

Abstract

Antimicrobial drug therapy in horses can lead to adverse effects across multiple body systems, with specific age groups, such as foals, at particular risk. Certain antimicrobial drugs, such as penicillins, aminoglycosides, macrolides, tetracyclines, and trimethoprim-sulfonamide combinations, are commonly implicated. This review explores the mechanisms behind these adverse reactions, emphasizing the importance of judicious antimicrobial drug use. This review also underscores the need for a centralized pharmacovigilance system to improve drug safety and adverse event reporting for veterinary medicine.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41058334/