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Peer-reviewed veterinary case report

Adverse reactions to drugs in a veterinary hospital.

Journal:
Journal of the American Veterinary Medical Association
Year:
1977
Authors:
Ndiritu, C G & Enos, L R

Plain-English summary

Over the course of a year, a veterinary hospital reviewed 130 cases where pets had suspected bad reactions to medications. In 66 of these cases, there was enough evidence to show that the medication was likely the cause of the reaction. Most of these reactions were linked to antibiotics, medications for parasites, and anesthetics. In 28 cases, the pets recovered on their own without needing extra treatment, but sadly, four animals died because of their reactions to the drugs. The study highlighted the need for veterinarians to be more aware of these potential drug reactions to improve safety and gather better information.

Abstract

In a one-year period (July 1, 1975, through June 30, 1976), 130 cases of suspected adverse drug reactions were reviewed in the Veterinary Medical Teaching Hospital, School of Veterinary Medicine, Davis, Ca. Sixty-six of these cases had sufficient evidence to link the reaction to the medication administered. Most of the reactions were attributed to anti-infective agents (antibiotics and parasiticides) and to anesthetics and related drugs. In 28 (42.4%) of the cases, uncomplicated recovery occurred without supportive medication. Four animals (6.1%) died as a direct result of adverse drug reactions. It was concluded that a higher degree of adverse drug reaction awareness is needed in the veterinary profession to enable the accumulation of meaningful data.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/893217/