Peer-reviewed veterinary case report
Afobazole Alleviates Cognitive Rigidity in Experimental Model of Autism Spectrum Disorders.
- Journal:
- Bulletin of experimental biology and medicine
- Year:
- 2019
- Authors:
- Kapitsa, I G et al.
- Affiliation:
- V. V. Zakusov Research Institute of Pharmacology
- Species:
- rodent
Abstract
Afobazole (10 mg/kg) alleviated cognitive rigidity in BALB/c mice, a phenotypic model of autism spectrum disorders. It improved spatial memory and retraining in T-maze with drinking reinforcement and restored the retrieval of acquired skill during reversal learning in Morris water maze.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31776949/