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Peer-reviewed veterinary case report

Aging in the canine and feline brain.

Journal:
The Veterinary clinics of North America. Small animal practice
Year:
2014
Authors:
Vite, Charles H & Head, Elizabeth
Affiliation:
Department of Clinical Studies · United States

Abstract

Aging dogs and cats show neurodegenerative features that are similar to human aging and Alzheimer disease. Neuropathologic changes with age may be linked to signs of cognitive dysfunction both in the laboratory and in a clinic setting. Less is known about cat brain aging and cognition and this represents an area for further study. Neurodegenerative diseases such as lysosomal storage diseases in dogs and cats also show similar features of human aging, suggesting some common underlying pathogenic mechanisms and also suggesting pathways that can be modified to promote healthy brain aging.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/25441628/