Albendazole and Triclabendazole Used as Treatment for Fasciolosis in Sheep.

Abstract

The effects of Albendazole and Triclabendazole on 12 adult Pelibuey ovines infected by Fasciola hepatica in the province of Camagüey, Cuba, were evaluated. A reduction and fecal egg count test was performed. Two groups of animals were made for critical study. On day 0 (D0), the animals in group 1 were given Albendazole orally, and group 2 received Triclabendazole. The fecal samples were collected (rectal) on days 0 (D0), 14 (D14), and 28 (D28), after treatment. The McMaster technique was used for F. hepatica egg count using a ZnCl 2 solution (1.5 g/ml), at 10 eggs per stool gram. The groupʼs mean results first, and the egg reduction per cent later, were calculated. On D14, 98.17 % egg reduction was observed in group 1, and 79.58 % in group 2. However, on D28, group 1 underwent 33 % reduction, whereas group 2 experienced 90.39 %. The treatment using Triclabendozole was more effective for F. hepatica.