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Peer-reviewed veterinary case report

Alzheimer's defense: brain CD8T cells in action.

Journal:
Trends in immunology
Year:
2023
Authors:
Hu, Dan
Affiliation:
Brigham and Women's Hospital and Harvard Medical School · United States

Abstract

In a remarkable new study, Su et al. have shown that a specific subpopulation of CD8T cells, attracted to brain lesion sites and expanded via microglia-CD8T cell CXCL16-CXCR6 intercellular communication, can curb Alzheimer's disease (AD)-related pathology in mouse models.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/37945503/