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Peer-reviewed veterinary case report

Amino acid and mineral levels in hyperthyroid and Siamese cats

By Sabatino, B R et al.·Published in Journal of veterinary internal medicine·2013·University of Tennessee College of Veterinary Medicine·View original on PubMed

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Original publication title: Amino acid, iodine, selenium, and coat color status among hyperthyroid, Siamese, and age-matched control cats.

Species:
cat

Plain-English summary

A group of 27 cats, including 12 with hyperthyroidism and 15 without, were studied to see if their blood levels of certain amino acids, iodine, and selenium were different. The researchers found that while hyperthyroid cats had lower levels of L-glutamine compared to the control group, overall, there were no significant differences in the other nutrients measured. This suggests that factors like coat color and these specific nutrients do not play a major role in the development of hyperthyroidism in cats. The findings can help veterinarians understand more about this common condition in older cats.

People also search for: hyperthyroidism in cats symptoms · Siamese cat health issues · cat diet for hyperthyroidism · low L-glutamine in cats · iodine levels in cats

Abstract

BACKGROUND: Hyperthyroidism is common among older cats, but its pathogenesis remains poorly understood. Siamese and Himalayan cats have a reduced risk of hyperthyroidism compared with domestic short-hair cat breeds. A mechanism of risk reduction in pointed-coat breeds is unknown. OBJECTIVES: To determine if tyrosine, phenylalanine, iodine, or selenium blood concentrations are altered in hyperthyroid cats and to describe the plasma amino acid profiles of client-owned cats with naturally occurring hyperthyroidism. ANIMALS: Twenty-seven client-owned cats with (n = 12) and without (n = 15) hyperthyroidism were studied. METHODS: Cross-sectional study. Hyperthyroid cats were prospectively recruited among cats presenting for radioiodine therapy. Control cats were recruited among pets of hospital personnel. Blood was collected for total thyroxine, plasma amino acid, selenium, and iodine determination. Coat color (8 white or pointed; 19 dark), breed, and diet history were recorded. RESULTS: Tyrosine, phenylalanine, iodine, and selenium levels were not significantly different among light or dark cats or cats with or without hyperthyroidism (P > .05). Plasma amino acid profiles of hyperthyroid cats and control cats were similar, and neither group was deficient in any of the amino acids. L-glutamine was significantly lower in cats with hyperthyroidism (mean &#xb1; SD: 648 &#xb1; 193) compared with control cats (816 &#xb1; 134; P < .05). CONCLUSIONS AND CLINICAL IMPORTANCE: Altered tyrosine, iodine, and selenium metabolism were not associated with coat color or hyperthyroidism in pointed or light coat-colored cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23952659/