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Peer-reviewed veterinary case report

Amniotic membrane surgery helps heal corneal sequestrum in cats

By Barachetti, Laura et al.·Published in Veterinary ophthalmology·2010·Dipartimento di Scienze Cliniche Veterinarie, Italy·View original on PubMed

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Original publication title: Amniotic membrane transplantation for the treatment of feline corneal sequestrum: pilot study.

Species:
cat

Plain-English summary

A group of six cats with corneal sequestrum (a painful eye condition) underwent surgery to remove the affected tissue and received a transplant of amniotic membrane to help heal the eye. After the procedure, five out of seven eyes showed good healing with minimal scarring and no recurrence of the sequestrum over a follow-up period of 3 to 9 months. However, two eyes had complications, including one that developed a serious issue with the transplanted membrane. Overall, the amniotic membrane transplant was effective for most cats, improving their eye health and vision.

People also search for: cat eye problems treatment · corneal sequestrum in cats · amniotic membrane for cat eyes

Abstract

OBJECTIVES: To describe and evaluate the use of equine amniotic membrane trans-plantation after lamellar keratectomy for the treatment of corneal sequestrum in cats. METHODS: Six cats (seven eyes) of various breed and ages with corneal sequestra were treated surgically with lamellar keratectomy and amniotic membrane transplantation. All the sequestra and a small piece of the amniotic membranes used for each surgery were submitted for histopathologic examination. RESULTS: Five of the seven eyes showed minimal level of scarring in the cornea and good transparency. No recurrences of the sequestra have been noted during the follow-up period (3-9 months). One eye had necrosis of the amniotic membrane 2 weeks after the surgery. The sequestrum of this eye showed a high level of bacterial contamination on histopathology. Three months later the same cat developed a descemetocele in the area where the necrotic amniotic membrane was rejected. A second eye developed a perforation under the amniotic membrane two weeks after the surgery. The sequestrum of this eye was deep and without vascularization. CONCLUSION: Amniotic membrane transplantation after lamellar keratectomy was a valid procedure for surgical treatment of corneal sequestrum in cats. The procedure resulted in excellent cosmesis and functional vision in five of seven eyes; although case selection is important, particularly to exclude the very deep and non-vascularized sequestra.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20840111/