Peer-reviewed veterinary case report
Brain tumor affecting optic nerve and hypothalamus in a Boxer dog
By Sisó, S et al.·Published in Veterinary pathology·2003·Department of Animal Medicine and Surgery, Spain·View original on PubMed →
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Original publication title: An anaplastic astrocytoma (optic chiasmatic-hypothalamic glioma) in a dog.
- Species:
- dog
Plain-English summary
A 3.5-year-old male Boxer was diagnosed with a tumor affecting his optic nerve, which also involved the surrounding areas of the brain. This condition caused significant issues with his vision and overall health. The tumor was identified as an anaplastic astrocytoma, a type of brain tumor. Unfortunately, the treatment options for this type of tumor can be limited, and the prognosis varies depending on the individual case. It's important for pet owners to discuss any concerning symptoms, like vision changes or behavioral shifts, with their veterinarian for proper evaluation and care.
People also search for: dog brain tumor symptoms · Boxer dog vision problems · treatment for dog optic nerve tumor
Abstract
A tumor located in the optic nerve extended through the optic chiasm, involving the hypophysis and the hypothalamic area in a 3.5-year-old male Boxer dog. It showed a biphasic pattern in which numerous highly fibrillated, well-differentiated pilocytic areas were intermingled with pleomorphic, microcystic tumor tissue. Immunohistochemical analysis of the tumor revealed that most of the neoplastic cells were immunoreactive for S-100 protein, with less intensity for glial fibrillary acidic protein (GFAP) and vimentin. A diagnosis of anaplastic astrocytoma was made on the basis of the histopathologic findings and immunohistochemical results. Moreover, there were similarities with the malignant variant of pilocytic astrocytoma described in human adults as an optic chiasmatic-hypothalamic glioma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12949415/