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Peer-reviewed veterinary case report

Emulsion lowers skin pH and inflammation in dogs with skin damage

By Pin, D et al.·Published in Journal of comparative pathology·2014·Interactions Cellules Environnement UPSP 2011.03.101, France·View original on PubMed

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Original publication title: An emulsion restores the skin barrier by decreasing the skin pH and inflammation in a canine experimental model.

Species:
dog

Plain-English summary

Five healthy beagle dogs had their skin barrier disrupted to test a product called Douxo Calm Mousse. The mousse was applied daily for five days on one side of their bodies, while the other side was left untreated. Although the product didn't change the amount of water lost through the skin, it did help keep the skin's pH at a healthy level and reduced inflammation, especially after multiple uses. This suggests that Douxo Calm Mousse can be helpful for improving skin health in dogs.

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Abstract

The aim of this study was to investigate the effect of Douxo(®) Calm Mousse (Sogeval, Laval, France) on restoration of the skin barrier in a canine model of barrier disruption. Tape strips were performed, daily for 6 days, on the lateral thorax of five healthy beagle dogs. Douxo(®) Calm Mousse was applied daily for 5 days to one side of the thorax and the opposite side was left untreated. The effects of treatment were evaluated by measurement of transepidermal water loss (TEWL) and pH and by histological assessment of disrupted skin at various times during barrier repair. Although no effect on TEWL was observed, Douxo(®) Calm Mousse maintained an acidic pH after three applications and reduced skin inflammation, which was most pronounced after five applications. The results of the study suggest that Douxo(®) Calm Mousse exerts a beneficial effect on barrier restoration and on markers of inflammation.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24975893/