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Peer-reviewed veterinary case report

An enzyme-free amplification strategy based on two-photon fluorescent carbon dots for monitoring miR-9 in live neurons and brain tissues of Alzheimer's disease mice.

Journal:
Chemical communications (Cambridge, England)
Year:
2020
Authors:
Wu, Wenxiao et al.
Affiliation:
Department of Chemistry · China
Species:
rodent

Abstract

An enzyme-free amplification strategy based on two-photon fluorescent carbon dots for monitoring miR-9 in live neurons and brain tissues of Alzheimer's disease (AD) mice. Notably, using our developed probe, miR-9 was found to be up-regulated in early onset AD, while it was found to be down regulated to lower than the normal level in late onset AD.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/32543623/