Peer-reviewed veterinary case report
Feline plasmacytic pododermatitis not linked to tested infections
By Bettenay, S V et al.·Published in Veterinary pathology·2007·Tierdermatologie Oberhaching, Germany·View original on PubMed →
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Original publication title: An immunohistochemical and polymerase chain reaction evaluation of feline plasmacytic pododermatitis.
- Species:
- cat
Plain-English summary
A group of cats with a skin condition called plasmacytic pododermatitis (which causes inflammation and swelling in the footpads) underwent skin biopsies to check for infections. The tests showed no signs of bacteria or fungi in the affected tissues, and DNA tests for several common pathogens also came back negative. This suggests that the condition may not be caused by an infection. The cats were followed for 12 to 36 months, but the study did not specify any treatments or outcomes.
People also search for: cat footpad swelling treatment · feline pododermatitis causes · cat skin infection symptoms
Abstract
Sections of 14 skin biopsies of cats with plasmacytic pododermatitis and a clinical follow-up of 12-36 months were stained with a polyclonal anti-Mycobacterium bovis (Bacille Calmette-Guerin = BCG) antibody cross-reactive to a broad spectrum of fungi and bacteria. All sections were negative for organisms within the actual footpad tissue with the anti-BCG antibody stains. Polymerase chain reaction (PCR) assays that amplify the DNA of Bartonella spp., Ehrlichia spp., Anaplasma phagocytophilum, Chlamydophila felis, Mycoplasma spp., Toxoplasma gondii, and feline herpesvirus 1 (FHV-1) were applied to tissue digests. DNA of those pathogens assessed was not amplified from tissue.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17197627/