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Peer-reviewed veterinary case report

Canine coronavirus outbreak causing diarrhea and weakness in Greek

By Ntafis, Vasileios et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2010·Agricultural University of Athens·View original on PubMed

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Original publication title: An outbreak of canine coronavirus in puppies in a Greek kennel.

Species:
dog

Plain-English summary

A group of puppies in a Greek kennel showed signs of diarrhea, lack of appetite, weakness, and dehydration, with one puppy sadly passing away. Testing revealed that all 11 puppies were infected with canine coronavirus type II, and one puppy also had a dual infection with canine parvovirus. This outbreak was notable as it was the first confirmed case of canine coronavirus in Greece. The puppies received supportive care, which is typically necessary for managing such infections, but the specific outcomes for each puppy were not detailed.

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Abstract

Canine coronavirus (CCoV) is usually the cause of mild gastroenteritis in dogs and is known to have spread worldwide. However, to date, no CCoV cases have been confirmed in Greece. In the present work, the authors investigated an outbreak of enteritis in puppies from a Greek kennel for the presence of CCoV. Dogs were presented with clinical signs of diarrhea, anorexia, weakness, depression, dehydration, and 1 death. Canine coronavirus type II was detected by reverse transcription nested polymerase chain reaction in all 11 puppies, whereas 1 puppy presented dual infection with CCoV type II and canine parvovirus 2. Surprisingly, sequence analysis of the samples revealed higher similarity to the pantropic CCoV II strain CB/05 than to other reference strains, in the most variable region of the S gene.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20224103/