Peer-reviewed veterinary case report
Newborn foal with ovarian mass - what does it mean?
By Machida, N et al.·Published in Journal of comparative pathology·2001·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: An ovarian interstitial cell hamartoma in a newborn foal.
- Species:
- horse
Plain-English summary
A thoroughbred foal was found to have a growth on its left ovary called an ovarian interstitial cell hamartoma, which is a type of benign tumor. Unfortunately, the foal died just 14 hours after birth due to a condition known as nutritional myopathy, or white-muscle disease. During the examination after death, a pale brown, mushroom-shaped mass was discovered on the ovary, and it was made up of densely packed cells similar to those found in a developing ovary. The findings indicated that the mass was indeed an ovarian interstitial cell hamartoma. Sadly, the treatment options were not applicable in this case due to the foal's early death.
Abstract
A case of congenital ovarian interstitial cell hamartoma in a thoroughbred foal that died of apparent nutritional myopathy (white-muscle disease) 14 h after birth is described. An incidental finding at necropsy was a pale brown, mushroom-shaped, pedunculated mass (6 x 4 x 3 cm) attached to the left ovary. On the cut surface, the mass had a peripheral rim of dense parenchyma (3-5 mm wide), surrounding a pale gelatinous core. Histologically, the mass consisted of a peripheral zone of densely packed large cells that were quite similar, morphologically, to fetal ovarian interstitial cells, and a central area of small nests of similar cells scattered within an extremely loose connective tissue matrix. Immunohistochemically, intracytoplasmic positive labelling for inhibin was detected in these cells. These observations suggest that the lesion was an ovarian interstitial cell hamartoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11798250/