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Peer-reviewed veterinary case report

An overview of infectious bursal disease.

Journal:
Archives of virology
Year:
2012
Authors:
Mahgoub, Hebata Allah et al.
Affiliation:
Mansoura University
Species:
bird

Abstract

Infectious bursal disease (IBD) is a viral immunosuppressive disease of chickens attacking mainly an important lymphoid organ in birds [the bursa of Fabricius (BF)]. The emergence of new variant strains of the causative agent [infectious bursal disease virus (IBDV)] has made it more urgent to develop new vaccination strategies against IBD. One of these strategies is the use of recombinant vaccines (DNA and viral-vectored vaccines). Several studies have investigated the host immune response towards IBDV. This review will present a detailed background on the disease and its causative agent, accompanied by a summary of the most recent findings regarding the host immune response to IBDV infection and the use of recombinant vaccines against IBD.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22707044/