Peer-reviewed veterinary case report
Bernese mountain dog with chronic vomiting and weight loss
By Gianella, P et al.·Published in Schweizer Archiv fur Tierheilkunde·2015·View original on PubMed →
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Original publication title: An unusual case of intestinal leiomyositis in a Bernese mountain dog.
- Species:
- dog
Plain-English summary
A 1-year-old female Bernese mountain dog was brought to the vet after losing weight and experiencing vomiting, constipation, and a swollen belly for three months. Tests showed severe damage to the muscles in her intestines, leading to a diagnosis of chronic idiopathic intestinal pseudo-obstruction, a condition where the intestines can't properly move food. Unfortunately, the dog did not respond well to treatment with immunosuppressive medications, and she was humanely euthanized.
People also search for: Bernese mountain dog vomiting · dog weight loss and constipation · intestinal problems in dogs treatment
Abstract
A 1-year-old, female Bernese mountain dog was presented to the Veterinary Teaching Hospital of Turin University with a 3-month history of weight loss, intermittent anorexia, vomiting, constipation, and abdominal distension. Full-thickness biopsies from the stomach, duodenum, jejunum and ileum were collected for histological and immunohistochemical examination. Microscopic lesions displayed severe diffuse degeneration and loss of leiomyocytes, with lymphocytic leiomyositis, fibroplasia, angiogenesis, severe diffuse neuronal atrophy, and ganglioneuritis in the myenteric (Auerbach's) plexus. A diagnosis of chronic idiopatic intestinal pseudo-obstruction was made. Response to immunosuppressive therapy was poor and the dog was humanely euthanized. Unique findings were mononuclear infiltration composed predominantly of B-cell, angiogenesis and weak immunoreactivity for neuron-specific enolase.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26897772/