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Peer-reviewed veterinary case report

Analysis of Dual-Energy Computed Tomography Imaging for the Evaluation of Lymph Node Metastasis in Canine Anal Sac Gland Adenocarcinoma: A Case Report.

Journal:
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Year:
2026
Authors:
Goda, Yoshimichi et al.
Affiliation:
Department of Companion Animal Clinical Sciences · Japan
Species:
dog

Plain-English summary

A 9-year-old neutered male miniature schnauzer was brought to the veterinary clinic because he was drinking and urinating a lot, had high calcium levels, low phosphorus levels, and elevated levels of a specific protein related to parathyroid hormone. Imaging tests showed a mass in his left anal gland and swelling in two nearby lymph nodes. After surgery to remove the mass, it was found to be anal sac gland adenocarcinoma, which had spread to the lymph nodes. The imaging tests helped confirm the diagnosis and showed that they could be useful for spotting cancer spread to lymph nodes. The treatment involved surgery, and the findings suggest that the imaging method can be helpful in similar cases.

Abstract

A 9-year-old neutered male miniature schnauzer was referred to our facility with polyuria, polydipsia, persistent hypercalcemia, hypophosphatemia, and elevated parathyroid hormone-related protein. Dual-energy computed tomography (DECT) imaging revealed a mass in the left anal gland (LAG) and enlargement of the left medial iliac lymph node (LML) and the left internal iliac lymph node (LIL). The mass was surgically removed, and the histopathological diagnosis was anal sac gland adenocarcinoma, with metastasis to the LML and LIL. The pathological findings were concordant with those obtained from our evaluation of the spectral Hounsfield unit curve and iodine concentration DECT imaging. DECT analysis may be useful for identifying metastatic lymph nodes.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41622597/