Peer-reviewed veterinary case report
Analysis of IMP-1 type metallo-β-lactamase-producing Acinetobacter radioresistens isolated from companion animals.
- Journal:
- Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
- Year:
- 2017
- Authors:
- Kimura, Yui et al.
- Affiliation:
- Miyamoto Animal Hospital · Japan
Plain-English summary
Researchers found a type of bacteria called Acinetobacter radioresistens, which produces an enzyme that makes it resistant to certain antibiotics, in a dog with a bladder infection (cystitis) and a cat with an eye infection (conjunctivitis). This bacteria was resistant to all tested beta-lactam antibiotics but responded well to gentamicin, amikacin, and minocycline. In fact, one of the two strains also responded to ciprofloxacin and levofloxacin. Both the dog and cat were successfully treated with tetracyclines and fluoroquinolones, which worked because the bacteria were sensitive to these medications. This is the first report of this resistant bacteria being found in pets, highlighting the need for veterinarians to be aware of such organisms to prevent their spread.
Abstract
IMP-1 type metallo-β-lactamase-producing (MBL-producing) Acinetobacter radioresistens was isolated from a dog with cystitis and a cat with conjunctivitis. The MBL-producing A. radioresistens isolates were resistant to all of the β-lactam antibiotics used in the sensitivity tests, but were susceptible to gentamicin, amikacin, and minocycline. Also, one of the two strains of A. radioresistens was susceptible to ciprofloxacin and levofloxacin. These two cases were cured by administration of tetracyclines and fluoroquinolones, which elicited a positive result in the sensitivity tests. This report of the isolation of MBL-producing A. radioresistens in companion animals is the first in the world. To prevent the proliferation of MBL-producing bacteria, veterinary hospitals need to be aware of the behavior of MBL-producing organisms.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28408304/