Peer-reviewed veterinary case report
Anaphylaxis and death risk after rabies vaccine in dogs in Japan
By Yoshida, Megumi et al.·Published in The Journal of veterinary medical science·2021·Azabu University, Japan·View original on PubMed →
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Original publication title: Anaphylaxis after rabies vaccination for dogs in Japan.
- Species:
- dog
Plain-English summary
A dog in Japan experienced a severe allergic reaction called anaphylaxis after receiving a rabies vaccination. Out of 317 cases studied over 15 years, 109 dogs had anaphylaxis, and unfortunately, 71 of those dogs did not survive. While these reactions are rare, they can be serious, so it's important for veterinarians to be ready to handle such emergencies. If your dog is due for a rabies vaccine, discuss any concerns with your vet to ensure they are prepared.
People also search for: dog rabies vaccine side effects · dog allergic reaction vaccine · what to do if my dog has anaphylaxis
Abstract
Severe adverse reactions after rabies vaccination in dogs were examined from 317 cases reported to the Ministry of Agriculture, Forestry and Fisheries (MAFF) in Japan during 15-year period from April 2004 to March 2019. We found that 109 of the 317 dogs showed anaphylaxis (0.15/100,000 vaccinated dogs), and 71 of the 109 cases of anaphylaxis resulted in death (0.10/100,000 vaccinated dogs). We measured bovine serum albumin (BSA) in four commercially available rabies vaccines and found the levels ranged from 0.1 to 16.6 µg/dose. Our survey showed that the rate of anaphylaxis to rabies vaccines in dogs is rare, although some cases of anaphylaxis resulted in death. Veterinarians should be well prepared to deal with vaccine-associated anaphylaxis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34108336/