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Peer-reviewed veterinary case report

Cat anaphylaxis and death risk after vaccination in Japan

By Yoshida, Megumi et al.·Published in The Journal of veterinary medical science·2022·Azabu University, Japan·View original on PubMed

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Original publication title: Anaphylaxis after vaccination for cats in Japan.

Species:
cat

Plain-English summary

A study found that a significant number of cats in Japan experienced severe allergic reactions, known as anaphylaxis, after receiving vaccinations. Out of 316 reported cases, 130 cats showed signs of anaphylaxis, and unfortunately, 99 of those cats did not survive. The research highlights the importance of veterinarians being prepared to handle these serious reactions, which can occur after vaccination. It also suggests that certain components in vaccines may contribute to these allergic responses.

People also search for: cat vaccination side effects · cat anaphylaxis symptoms · what to do if my cat has a reaction to a vaccine

Abstract

Severe adverse reactions in cats after vaccination were examined from 316 cases reported to the Ministry of Agriculture, Forestry and Fisheries (MAFF) in Japan during 15-year period from April 2004 to March 2019. We found that 130 (41%) showed anaphylaxis, and 99 (76%) of the 130 cases of anaphylaxis resulted in death. Veterinarians should be well prepared to deal with vaccine-associated anaphylaxis in cats. Bovine serum albumin (BSA) as indicator of purification was detected at high levels in commercially available feline vaccines. BSA might derive from fetal calf serum in culture media. This study provides useful information about anaphylaxis including critical details of the potential clinical signs associated with adverse events to feline vaccination.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34789596/